EVOLUTION OF THE ECONOMIC RESULTS AND THE STRUCTURE OF FARMS: AN ANALYSIS THROUGH THE BOOK-KEEPING DATA IN CENTRAL AND NORTHERN ITALY

The latest orientations of the CAP have had remarkable and wide-spread effects on the whole agri-food sector. It has deeply influenced the entrepreneurs' choices, with reference both to the production techniques and to the business organization. The changes have had inevitable reflexes on the economic results of the firms, thus determining adaptations regarding both the structure and the amount of inputs. In this paper, an analysis of the book-keeping results of agricultural enterprises of Northern and Central Italy is carried out. We try to underline and analyze the evolution of the economic results and the main structural and organizational elements in the firms. The accountancy data of a group of firms located in the Veneto, Emilia-Romagna and Tuscany regions, referred to the period 1994-2000, are taken into consideration. These firms seems to adequately represent the main type of farming: field crops, fruit-growing, wine-growing, husbandry. The study is aimed at underlining the influence of the EU payments on the profitability and the changes in the value distribution between the various input suppliers.Farm Management,

Converged Digital TV Services: The Role of Middleware and Future Directions of Interactive Television

The migration from analog to digital of the broadcasting technologies, already well consolidated for satellite systems, is becoming a reality also for terrestrial transmission. Digital Terrestrial Television (DTT) is also evolving to offer interactive services and a degree of flexibility which can be exploited to offer tailored applications to users which include, for instance interactivity, different levels of personalization, and innovative location-based, as well as context-aware, services. A clear example of this trend is given by the rising success of the Internet Protocol Television (IPTV) which allows for a degree of flexibility on offered services unknown to the traditional broadcasting systems. In this framework, several satellite operators are starting to launch IPTV services using direct satellite links, as well as some terrestrial internet service providers are offering digital TV channels embedded in the IP streaming over XDSL. Furthermore, IPTV services are likely to be broadcast also wirelessly, exploiting advanced broadband access technologies such asWiMAX, LTE, or LTEA. Last, but not least, TV and broadcast services for mobile users have also been deployed in many countries using DVBH and will be soon available on an even broader scale thanks to its satellite counterpart, DVB-SH. In the near future, a set of different technologies able to offer personalized and customized services to different classes of users are expected in the area of wireless broadcasting and convergence of technologies is auspicious. This concept entails different levels of convergence, namely, at terminal level (one device fits all), at service level (convergence of traditional fixed, mobile, and broadcast services), and at transport and network level with a common and standardized set of protocols and at access layer thanks to the harmonic coexistence of different radio technologies. This special issue aims to capture the state-of-the-art research work concerning the integration of DTT/Satellite/IPTV systems for the broadcasting of multimedia and interactive services

The PTPN22 C1858T gene variant is associated with proinsulin in new-onset type 1 diabetes

<p>Abstract</p> <p>Background</p> <p>The protein tyrosine phosphatase nonreceptor type 2 (<it>PTPN22</it>) has been established as a type 1 diabetes susceptibility gene. A recent study found the C1858T variant of this gene to be associated with lower residual fasting C-peptide levels and poorer glycemic control in patients with type 1 diabetes. We investigated the association of the C1858T variant with residual beta-cell function (as assessed by stimulated C-peptide, proinsulin and insulin dose-adjusted HbA_1c), glycemic control, daily insulin requirements, diabetic ketoacidosis (DKA) and diabetes-related autoantibodies (IA-2A, GADA, ICA, ZnT8Ab) in children during the first year after diagnosis of type 1 diabetes.</p> <p>Methods</p> <p>The C1858T variant was genotyped in an international cohort of children (n = 257 patients) with newly diagnosed type 1 diabetes during 12 months after onset. We investigated the association of this variant with liquid-meal stimulated beta-cell function (proinsulin and C-peptide) and antibody status 1, 6 and 12 months after onset. In addition HbA_1cand daily insulin requirements were determined 1, 3, 6, 9 and 12 months after diagnosis. DKA was defined at disease onset.</p> <p>Results</p> <p>A repeated measurement model of all time points showed the stimulated proinsulin level is significantly higher (22%, p = 0.03) for the T allele carriers the first year after onset. We also found a significant positive association between proinsulin and IA levels (est.: 1.12, p = 0.002), which did not influence the association between <it>PTPN22 </it>and proinsulin (est.: 1.28, p = 0.03).</p> <p>Conclusions</p> <p>The T allele of the C1858T variant is positively associated with proinsulin levels during the first 12 months in newly diagnosed type 1 diabetes children.</p